Drug to Drug Interactions

Please note: X means there is a potential drug to drug interaction.

Concomitant Medications Sofosbuvir Ledipasvir Paritaprevir / Ritonavir / Ombitasvir + Dasabuvir Simeprevir
Acid-reducing agents X X
Digoxin X X
Anticonvulsants X X X X
Simeprevir X
Herbals: St. John’s Wort X X
Herbals: Milk Thistle X X
Rifamycin antimicrobials X X X X
Gemfibrozil X
Statins X X X
Other Antiarrythmics X X
Macrolide Antimicrobials X
Azole Antifungals X X
Calcium Channel Blockers X X
Glucocorticoids X (inhaled, intranasal) X
Cisapride X X
Calcineurin Inhibitors X X
Sedatives X X
Alfuzosin/Tamsulosin X
Ergot derivatives X
Ethinyl Estradiol-Containing Products X
Pimozide X
Phosphodiesterase Type 5 Inhibitors X X
Salmeterol X
Furosemide X
Buprenorphine/Naloxone X
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